This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 2004 Jun;113(6):1776-82.

doi: 10.1542/peds.113.6.1776.

Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle

Thomas W Sedlak¹, Solomon H Snyder

Affiliations

PMID: 15173506
DOI: 10.1542/peds.113.6.1776

Review

Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle

Thomas W Sedlak et al. Pediatrics. 2004 Jun.

. 2004 Jun;113(6):1776-82.

doi: 10.1542/peds.113.6.1776.

Authors

Thomas W Sedlak¹, Solomon H Snyder

Affiliation

¹ Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA. ssnyder@bs.jhmi.edu

PMID: 15173506
DOI: 10.1542/peds.113.6.1776

No abstract available

PubMed Disclaimer

Comment in

Conflict of interest and purpose in bilirubin screening.
Lavin A. Lavin A. Pediatrics. 2004 Oct;114(4):1133; author reply 1133-4. doi: 10.1542/peds.2004-1408. Pediatrics. 2004. PMID: 15466131 No abstract available.
Bilirubin the beneficent.
McDonagh A. McDonagh A. Pediatrics. 2004 Dec;114(6):1741-2; author reply 1742-3. doi: 10.1542/peds.2004-1426. Pediatrics. 2004. PMID: 15574652 No abstract available.
Impact of serum bilirubin on human diseases.
Vítek L. Vítek L. Pediatrics. 2005 May;115(5):1411-2. doi: 10.1542/peds.2004-1796. Pediatrics. 2005. PMID: 15867053 No abstract available.

Similar articles

Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase.
Maghzal GJ, Leck MC, Collinson E, Li C, Stocker R. Maghzal GJ, et al. J Biol Chem. 2009 Oct 23;284(43):29251-9. doi: 10.1074/jbc.M109.037119. Epub 2009 Aug 18. J Biol Chem. 2009. PMID: 19690164 Free PMC article.
Biliverdin reductase: a major physiologic cytoprotectant.
Baranano DE, Rao M, Ferris CD, Snyder SH. Baranano DE, et al. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16093-8. doi: 10.1073/pnas.252626999. Epub 2002 Nov 27. Proc Natl Acad Sci U S A. 2002. PMID: 12456881 Free PMC article.
Bilirubin the beneficent.
McDonagh A. McDonagh A. Pediatrics. 2004 Dec;114(6):1741-2; author reply 1742-3. doi: 10.1542/peds.2004-1426. Pediatrics. 2004. PMID: 15574652 No abstract available.
Biliverdin reductase: new features of an old enzyme and its potential therapeutic significance.
Florczyk UM, Jozkowicz A, Dulak J. Florczyk UM, et al. Pharmacol Rep. 2008 Jan-Feb;60(1):38-48. Pharmacol Rep. 2008. PMID: 18276984 Free PMC article. Review.
Neuroprotective Roles of the Biliverdin Reductase-A/Bilirubin Axis in the Brain.
Paul BD, Pieper AA. Paul BD, et al. Biomolecules. 2024 Jan 28;14(2):155. doi: 10.3390/biom14020155. Biomolecules. 2024. PMID: 38397392 Free PMC article. Review.

See all similar articles

Cited by

Scalable production of biliverdin IXα by Escherichia coli.
Chen D, Brown JD, Kawasaki Y, Bommer J, Takemoto JY. Chen D, et al. BMC Biotechnol. 2012 Nov 23;12:89. doi: 10.1186/1472-6750-12-89. BMC Biotechnol. 2012. PMID: 23176158 Free PMC article.
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia.
Wang S, Lin Y, Zhou Z, Gao L, Yang Z, Li F, Wu B. Wang S, et al. Theranostics. 2019 Jul 9;9(18):5122-5133. doi: 10.7150/thno.35773. eCollection 2019. Theranostics. 2019. PMID: 31410205 Free PMC article.
Audiological and electrocochleography findings in hearing-impaired children with connexin 26 mutations and otoacoustic emissions.
Santarelli R, Cama E, Scimemi P, Dal Monte E, Genovese E, Arslan E. Santarelli R, et al. Eur Arch Otorhinolaryngol. 2008 Jan;265(1):43-51. doi: 10.1007/s00405-007-0412-z. Epub 2007 Aug 14. Eur Arch Otorhinolaryngol. 2008. PMID: 17701047
Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells.
Wójcik C, Rowicka M, Kudlicki A, Nowis D, McConnell E, Kujawa M, DeMartino GN. Wójcik C, et al. Mol Biol Cell. 2006 Nov;17(11):4606-18. doi: 10.1091/mbc.e06-05-0432. Epub 2006 Aug 16. Mol Biol Cell. 2006. PMID: 16914519 Free PMC article.
Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.
Cook-Mills JM, Marchese ME, Abdala-Valencia H. Cook-Mills JM, et al. Antioxid Redox Signal. 2011 Sep 15;15(6):1607-38. doi: 10.1089/ars.2010.3522. Epub 2011 May 11. Antioxid Redox Signal. 2011. PMID: 21050132 Free PMC article. Review.

See all "Cited by" articles

Publication types

Actions
Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

LinkOut - more resources

Full Text Sources
- Silverchair Information Systems
Other Literature Sources
- The Lens - Patent Citations Database