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Case Reports
. 1992 Jul;45(7):624-7.
doi: 10.1136/jcp.45.7.624.

Progressive multifocal leucoencephalopathy, sclerosing cholangitis, bronchiectasis and disseminated warts in a patient with primary combined immune deficiency

S A Misbah  1 , G P Spickett, A Zeman, M M Esiri, T B Wallington, J B Kurtz, H M Chapel
Affiliations
Case Reports

Progressive multifocal leucoencephalopathy, sclerosing cholangitis, bronchiectasis and disseminated warts in a patient with primary combined immune deficiency

S A Misbah et al. J Clin Pathol. 1992 Jul.

Erratum in

  • J Clin Pathol 1992 Oct;45(10):944

Abstract

A 24 year old man presented with an unusual primary combined immune deficiency syndrome characterised by a profound lymphopenia of CD4 cells, selective serum IgG2 subclass deficiency, poor polysaccharide antibody responses, disseminated warts, recurrent sinopulmonary infection and bronchiectasis. The developed progressive multifocal leucoencephalopathy (PML) in association with sclerosing cholangitis. Progressive multifocal leucoencephalopathy (PML) usually occurs as an opportunistic infection in patients with secondary defects in cellular immunity.

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