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Review
. 2004 Jun 15;221(1-2):99-104.
doi: 10.1016/j.jns.2004.02.020.

IgA monoclonal gammopathy of undetermined significance with peripheral neuropathy

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Review

IgA monoclonal gammopathy of undetermined significance with peripheral neuropathy

M M Mehndiratta et al. J Neurol Sci. .

Abstract

Monoclonal gammopathy of undetermined significance (MGUS) and peripheral neuropathy may be causally linked. In most cases, the M-protein is of IgG or IgM type. Peripheral neuropathy associated with IgA MGUS is uncommon, and there are limited reports. Here, we report a case of a 55-year-old male who was diagnosed to have symmetrical sensorimotor peripheral neuropathy associated with IgA MGUS with deposits of IgA-monoclonal protein in the myelin sheath.

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