Emerging therapeutic strategies for the management of dyslipidemia in patients with the metabolic syndrome
- PMID: 15178511
- DOI: 10.1016/j.amjcard.2004.02.006
Emerging therapeutic strategies for the management of dyslipidemia in patients with the metabolic syndrome
Abstract
The benefits of lipid-lowering therapy in significantly reducing cardiovascular events has been established in many at-risk populations. However, patients with the metabolic syndrome (MS) pose a challenge for clinical management. A high degree of residual risk exists in patients with the MS or diabetes mellitus, and this is of growing importance because of the increasing prevalence of obesity and its associated comorbidities in the world. As the MS has emerged as a major risk factor for both cardiovascular disease and diabetes, targeting treatment to achieve aggressive goals becomes paramount. This article reviews emerging therapeutic strategies for the management of dyslipidemia in patients with the MS.
Similar articles
-
Effects of lipid-altering treatment in diabetes mellitus and the metabolic syndrome.Am J Cardiol. 2004 Jun 3;93(11A):18C-26C. doi: 10.1016/j.amjcard.2004.02.002. Am J Cardiol. 2004. PMID: 15178513 Review.
-
Strategies in ongoing clinical trials to reduce cardiovascular disease in patients with diabetes mellitus and insulin resistance.Am J Cardiol. 2004 Jun 3;93(11A):27C-31C. doi: 10.1016/j.amjcard.2004.02.003. Am J Cardiol. 2004. PMID: 15178514 Review.
-
Role of surrogate markers in assessing patients with diabetes mellitus and the metabolic syndrome and in evaluating lipid-lowering therapy.Am J Cardiol. 2004 Jun 3;93(11A):32C-48C. doi: 10.1016/j.amjcard.2004.02.004. Am J Cardiol. 2004. PMID: 15178515 Review.
-
Advances in the management of hyperlipidemia-induced atherosclerosis.Expert Rev Cardiovasc Ther. 2008 Mar;6(3):369-83. doi: 10.1586/14779072.6.3.369. Expert Rev Cardiovasc Ther. 2008. PMID: 18327996 Review.
-
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines.J Am Coll Cardiol. 2004 Aug 4;44(3):720-32. doi: 10.1016/j.jacc.2004.07.001. J Am Coll Cardiol. 2004. PMID: 15358046 Review.
Cited by
-
Abrogation of postprandial triglyceridemia with dual PPAR α/γ agonist in type 2 diabetes mellitus: a randomized, placebo-controlled study.Acta Diabetol. 2020 Jul;57(7):809-818. doi: 10.1007/s00592-020-01487-8. Epub 2020 Feb 6. Acta Diabetol. 2020. PMID: 32030508 Clinical Trial.
-
Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease.BMC Med. 2007 Jul 19;5:20. doi: 10.1186/1741-7015-5-20. BMC Med. 2007. PMID: 17640385 Free PMC article.
-
Reversal of high dietary fructose-induced PPARalpha suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors.Nutr Metab (Lond). 2005 Aug 9;2:18. doi: 10.1186/1743-7075-2-18. Nutr Metab (Lond). 2005. PMID: 16091142 Free PMC article.
-
Effects of fenofibrate on atherogenic dyslipidemia in hypertriglyceridemic subjects.Clin Cardiol. 2006 Jun;29(6):268-73. doi: 10.1002/clc.4960290609. Clin Cardiol. 2006. PMID: 16796078 Free PMC article. Clinical Trial.
-
Tamoxifen alters the plasma concentration of molecules associated with cardiovascular risk in women with breast cancer undergoing chemotherapy.Oncologist. 2012;17(4):499-507. doi: 10.1634/theoncologist.2011-0369. Epub 2012 Apr 4. Oncologist. 2012. PMID: 22491005 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials