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Review
. 2004 Apr;59(4):251-4.

[Valdecoxib (Bextra)]

[Article in French]
A J Scheen  1 , M Malaise
Affiliations
  • PMID: 15182039
Free article
Review

[Valdecoxib (Bextra)]

[Article in French]
A J Scheen et al. Rev Med Liege. 2004 Apr.
Free article

Abstract

Valdecoxib (Bextra tablets of 10 mg and 20 mg) is a new non steroidal antiinflammatory drug (NSAID) that selectively inhibits COX-2 isoform of cyclo-oxygenase. It is indicated for the symptomatic treatment of osteoarthritis or rheumatoid arthritis (10 to 20 mg once a day) and for the treatment of primary dysmenorrhea (40 mg once a day). Valdecoxib is as efficacious as conventional non-COX-2 selective NSAIDs, but offers the advantage of a much better gastrointestinal tolerance. Valdecoxib has a prodrug that can be administered intravenously or intramuscularly (parecoxib, Dynastat) and has been developed for the short-term treatment of postsurgical pain.

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