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Review
. 2004 Mar;31(1):107-16.
doi: 10.1016/j.clp.2004.03.008.

Biomarkers of hypoxic brain injury in the neonate

Affiliations
Review

Biomarkers of hypoxic brain injury in the neonate

Giuseppe Buonocore et al. Clin Perinatol. 2004 Mar.

Abstract

The specific pathologic processes preceding the onset of irreversible cerebral injury seem to be a combination of several complex mechanisms due to the severity and duration of the insult to the biochemical modifications in the brain. An early diagnosis of the newborn at high risk for brain damage is relevant for preventive programs. Neuroprotective strategies will benefit from the detection of biochemical markers with high reliability and predictability for brain injury.

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