Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Jun;42(6):2866-9.
doi: 10.1128/JCM.42.6.2866-2869.2004.

Fatal case of toxic shock-like syndrome due to group C streptococcus associated with superantigen exotoxin

Tony M Korman  1 , Anthony Boers, Travis M Gooding, Nigel Curtis, Kumar Visvanathan
Affiliations
Review

Fatal case of toxic shock-like syndrome due to group C streptococcus associated with superantigen exotoxin

Tony M Korman et al. J Clin Microbiol. 2004 Jun.

Abstract

Group C streptococci have been reported to cause invasive disease similar to that classically associated with group A streptococcus (GAS). We describe a fatal case of toxic shock-like syndrome due to Streptococcus equi subsp. zooepidemicus. The causative organism did not possess any known GAS superantigen exotoxin genes but did show evidence of superantigen production.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Proliferation of PBMCs after stimulation for 3 days with culture supernatants from a non-toxin-producing GCS negative control strain, the patient's GCS isolate, and a toxin-producing GAS positive control strain. Each bar represents the mean and standard deviation of three assays. Note the marked dose-dependent proliferation produced by the patient's GCS and GAS supernatants compared to the negative controls.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Anzai, T., A. S. Sheoran, Y. Kuwamoto, T. Kondo, R. Wada, T. Inoue, and J. F. Timoney. 1999. Streptococcus equi but not Streptococcus zooepidemicus produces potent mitogenic responses from equine peripheral blood mononuclear cells. Vet. Immunol. Immunopathol. 67:235-246. - PubMed
    1. Artiushin, S. C., J. F. Timoney, A. S. Sheoran, and S. K. Muthupalani. 2002. Characterization and immunogenicity of pyrogenic mitogens SePE-H and SePE-I of Streptococcus equi. Microb. Pathog. 32:71-85. - PubMed
    1. Barnham, M., J. Kerby, R. S. Chandler, and M. R. Millar. 1989. Group C streptococci in human infection: a study of 308 isolates with clinical correlations. Epidemiol. Infect. 102:379-390. - PMC - PubMed
    1. Bateman, A. C., A. D. Ramsay, and A. P. Pallett. 1993. Fatal infection associated with group C streptococci. J. Clin. Pathol. 46:965-967. - PMC - PubMed
    1. Bradley, S. F., J. J. Gordon, D. D. Baumgartner, W. A. Marasco, and C. A. Kauffman. 1991. Group C streptococcal bacteremia: analysis of 88 cases. Rev. Infect. Dis. 13:270-280. - PubMed

LinkOut - more resources