Comment on

• Analysis of two human leukocyte antigen-linked polymorphic heat shock protein 70 genes in patients with severe sepsis.

  Schroeder S, Reck M, Hoeft A, Stüber F. Schroeder S, et al. Crit Care Med. 1999 Jul;27(7):1265-70. doi: 10.1097/00003246-199907000-00006. Crit Care Med. 1999. PMID: 10446818
• Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis.

  Fang XM, Schröder S, Hoeft A, Stüber F. Fang XM, et al. Crit Care Med. 1999 Jul;27(7):1330-4. doi: 10.1097/00003246-199907000-00024. Crit Care Med. 1999. PMID: 10446828
• High prevalence of hyperhomocysteinemia in critically ill patients.

  Schindler K, Zauner C, Buchmayer H, Födinger M, Wölfl G, Bieglmayer C, Heinz G, Wilfing A, Hörl WH, Sunder-Plassmann G. Schindler K, et al. Crit Care Med. 2000 Apr;28(4):991-5. doi: 10.1097/00003246-200004000-00013. Crit Care Med. 2000. PMID: 10809271
• G-protein beta3 subunit gene (GNB3) polymorphism 825C-->T in patients with hypertensive crisis.

  Buchmayer H, Sunder-Plassmann G, Hirschl MM, Kletzmayr J, Woisetschläger C, Laggner AN, Hörl WH, Födinger M. Buchmayer H, et al. Crit Care Med. 2000 Sep;28(9):3203-6. doi: 10.1097/00003246-200009000-00015. Crit Care Med. 2000. PMID: 11008983
• Gene variants of the bactericidal/permeability increasing protein and lipopolysaccharide binding protein in sepsis patients: gender-specific genetic predisposition to sepsis.

  Hubacek JA, Stüber F, Fröhlich D, Book M, Wetegrove S, Ritter M, Rothe G, Schmitz G. Hubacek JA, et al. Crit Care Med. 2001 Mar;29(3):557-61. doi: 10.1097/00003246-200103000-00015. Crit Care Med. 2001. PMID: 11373419
• Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis.

  Schlüter B, Raufhake C, Erren M, Schotte H, Kipp F, Rust S, Van Aken H, Assmann G, Berendes E. Schlüter B, et al. Crit Care Med. 2002 Jan;30(1):32-7. doi: 10.1097/00003246-200201000-00005. Crit Care Med. 2002. PMID: 11902285
• Can the interleukin-6 response to endotoxin be predicted? Studies of the influence of a promoter polymorphism of the interleukin-6 gene, gender, the density of the endotoxin receptor CD14, and inflammatory cytokines.

  Heesen M, Bloemeke B, Heussen N, Kunz D. Heesen M, et al. Crit Care Med. 2002 Mar;30(3):664-9. doi: 10.1097/00003246-200203000-00028. Crit Care Med. 2002. PMID: 11990931
• Association between a genomic polymorphism within the CD14 locus and septic shock susceptibility and mortality rate.

  Gibot S, Cariou A, Drouet L, Rossignol M, Ripoll L. Gibot S, et al. Crit Care Med. 2002 May;30(5):969-73. doi: 10.1097/00003246-200205000-00003. Crit Care Med. 2002. PMID: 12006789
• Genetic variation in proinflammatory and anti-inflammatory cytokine production in multiple organ dysfunction syndrome.

  Reid CL, Perrey C, Pravica V, Hutchinson IV, Campbell IT. Reid CL, et al. Crit Care Med. 2002 Oct;30(10):2216-21. doi: 10.1097/00003246-200210000-00007. Crit Care Med. 2002. PMID: 12394947
• Angiotensin converting enzyme DD genotype is associated with hypertensive crisis.

  Sunder-Plassmann G, Kittler H, Eberle C, Hirschl MM, Woisetschläger C, Derhaschnig U, Laggner AN, Hörl WH, Födinger M. Sunder-Plassmann G, et al. Crit Care Med. 2002 Oct;30(10):2236-41. doi: 10.1097/00003246-200210000-00010. Crit Care Med. 2002. PMID: 12394950
• Influence of interleukin-10 polymorphisms on interleukin-10 expression and survival in critically ill patients.

  Lowe PR, Galley HF, Abdel-Fattah A, Webster NR. Lowe PR, et al. Crit Care Med. 2003 Jan;31(1):34-8. doi: 10.1097/00003246-200301000-00005. Crit Care Med. 2003. PMID: 12544990
• Linkage disequilibrium between tumor necrosis factor (TNF)-alpha-308 G/A promoter and TNF-beta NcoI polymorphisms: Association with TNF-alpha response of granulocytes to endotoxin stimulation.

  Heesen M, Kunz D, Bachmann-Mennenga B, Merk HF, Bloemeke B. Heesen M, et al. Crit Care Med. 2003 Jan;31(1):211-4. doi: 10.1097/00003246-200301000-00032. Crit Care Med. 2003. PMID: 12545017