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. 2004 Jun 21;2(12):1679-81.
doi: 10.1039/b406488g. Epub 2004 May 13.

Complete functionalisation of small and large diameter bromopolystyrene beads; applications for solid-supported reagents, scavengers and diversity-oriented synthesis

Gemma L Thomas  1 , Mark Ladlow, David R Spring
Affiliations

Complete functionalisation of small and large diameter bromopolystyrene beads; applications for solid-supported reagents, scavengers and diversity-oriented synthesis

Gemma L Thomas et al. Org Biomol Chem. .

Abstract

Bromopolystyrene beads with diameters of up to 600 microm have been derivatized completely, via bromine-magnesium exchange and interception with electrophiles, to yield high quality solid-supported reagents, scavengers and solid supports for use in diversity-oriented synthesis.

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