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. 2004 Jun 15;10(12):1798-801.
doi: 10.3748/wjg.v10.i12.1798.

Severity of gastroesophageal reflux disease influences daytime somnolence: a clinical study of 134 patients underwent upper panendoscopy

Pál Demeter  1 , Katalin-Várdi Visy, Norá Gyulai, Róbert Sike, Tamás G Tóth, János Novák, Pál Magyar
Affiliations

Severity of gastroesophageal reflux disease influences daytime somnolence: a clinical study of 134 patients underwent upper panendoscopy

Pál Demeter et al. World J Gastroenterol. .

Abstract

Aim: To asses the relationship between severity of gastroesophageal refluxe disease and Epworth sleepiness scale as an indicator of daytime somnolence.

Methods: One hundred and thirty-four patients underwent an upper panendoscopy as indicated by the typical reflux symptoms and were also investigated with regard to somnolence. Sleepiness was evaluated by Epworth Sleepiness Scale, which was compared to the severity of endoscopic findings (Savary-Miller/modified by Siewert). Patients with psychiatric disorders or being on sedato-hypnotics as well as shift workers were excluded from the study. The relationship between the severity of the reflux disease and daytime somnolence was analyzed with the help of multivariate regression analysis.

Results: A positive tendency was found between the severity of the reflux disease and the corresponding Epworth Sleepiness Scale. In the case of the more severe type - Savary-Miller III - at least a mild hypersomnia was found. For this group daytime somnolence was significantly higher than in the case of the non-erosive type of Gastroesophageal Reflux Disease representing the mildest stage of reflux disease.

Conclusion: The severity of Gastroesophageal Reflux Disease influences daytime somnolence.

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References

    1. Pasricha PJ. Effect of sleep on gastroesophageal physiology and airway protective mechanisms. Am J Med. 2003;115 （Suppl 3A）:114S–118S. - PubMed
    1. Khoury RM, Camacho-Lobato L, Katz PO, Mohiuddin MA, Castell DO. Influence of spontaneous sleep positions on nighttime recumbent reflux in patients with gastroesophageal reflux disease. Am J Gastroenterol. 1999;94:2069–2073. - PubMed
    1. Penzel T, Becker HF, Brandenburg U, Labunski T, Pankow W, Peter JH. Arousal in patients with gastro-oesophageal reflux and sleep apnoea. Eur Respir J. 1999;14:1266–1270. - PubMed
    1. Ing AJ, Ngu MC, Breslin AB. Obstructive sleep apnea and gastroesophageal reflux. Am J Med. 2000;108(Suppl 4A):120S–125S. - PubMed
    1. Orr WC. Sleep-related breathing disorders: is it all about apnea. Chest. 2002;121:8–11. - PubMed