Review
doi: 10.1016/j.bjps.2004.02.012.
Composite tissue allotransplantation--a new era in plastic surgery?
Affiliations
- PMID: 15191817
- DOI: 10.1016/j.bjps.2004.02.012
Item in Clipboard
Review
Composite tissue allotransplantation--a new era in plastic surgery?
Br J Plast Surg.
2004 Jul.
Abstract
Composite tissue allotransplantation (CTA) holds great potential for reconstructive surgery. The recent hand transplants have made this a clinical reality. However, concerns about CTA have divided the medical community. The current transplants require life-long immunosuppression, which could place the recipients at risk of serious complications. In addition despite potent immunosuppression, chronic rejection may still negate any early favourable results. This article will outline the clinical experience of CTA, the major problems of the technique and the potential solutions to these problems.
Comment in
-
Give and take.Br J Plast Surg. 2004 Jul;57(5):379. doi: 10.1016/j.bjps.2004.05.001. Br J Plast Surg. 2004. PMID: 15191816 No abstract available.
Similar articles
-
Composite tissue allotransplantation: hand transplantation and beyond.J Am Acad Orthop Surg. 2010 Mar;18(3):127-31. doi: 10.5435/00124635-201003000-00001. J Am Acad Orthop Surg. 2010. PMID: 20190102 Review.
-
Composite tissue transplantation: a rapidly advancing field.Transplant Proc. 2008 Jun;40(5):1237-48. doi: 10.1016/j.transproceed.2008.04.003. Transplant Proc. 2008. PMID: 18589081 Free PMC article. Review.
-
Composite tissue allotransplantation and reconstructive surgery: first clinical applications.Ann Surg. 2003 Jan;237(1):19-25. doi: 10.1097/00000658-200301000-00004. Ann Surg. 2003. PMID: 12496526 Free PMC article. Review.
-
Current indications for hand and face allotransplantation.Transplant Proc. 2009 Mar;41(2):495-8. doi: 10.1016/j.transproceed.2009.01.065. Transplant Proc. 2009. PMID: 19328911
-
[Reconstructive surgery using composite tissue allografts: perspectives from the first clinical cases].Ann Chir Plast Esthet. 2002 Jun;47(3):222-31. doi: 10.1016/s0294-1260(02)00114-0. Ann Chir Plast Esthet. 2002. PMID: 12148230 French.
Cited by
-
Facial transplantation.BMJ. 2005 Dec 10;331(7529):1349-50. doi: 10.1136/bmj.331.7529.1349. BMJ. 2005. PMID: 16339221 Free PMC article. No abstract available.
-
Immune responses in transplantation: application to composite tissue allograft.Semin Plast Surg. 2007 Nov;21(4):226-33. doi: 10.1055/s-2007-991192. Semin Plast Surg. 2007. PMID: 20567675 Free PMC article.
-
Attitudes Toward Penile Transplantation Among Urologists and Health Professionals.Sex Med. 2018 Dec;6(4):316-323. doi: 10.1016/j.esxm.2018.06.003. Epub 2018 Jul 26. Sex Med. 2018. PMID: 30057121 Free PMC article.
-
Intraoperative Hemifacial Composite Flap Perfusion Assessment Using Spatial Frequency Domain Imaging: A Pilot Study in Preparation for Facial Transplantation.Ann Plast Surg. 2016 Feb;76(2):249-55. doi: 10.1097/SAP.0000000000000631. Ann Plast Surg. 2016. PMID: 26418791 Free PMC article.
-
The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection.PLoS One. 2013 Aug 5;8(8):e70968. doi: 10.1371/journal.pone.0070968. Print 2013. PLoS One. 2013. PMID: 23940676 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
