doi: 10.1016/j.vaccine.2003.11.073.
Enhancement of DNA vaccine potency in rhesus macaques by electroporation
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- PMID: 15193413
- DOI: 10.1016/j.vaccine.2003.11.073
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Enhancement of DNA vaccine potency in rhesus macaques by electroporation
Vaccine.
.
Abstract
The potency of an HIV DNA vaccine was enhanced in rhesus macaques by in vivo electroporation, as judged by increased onset, magnitude and duration of antibody and cell-mediated immune responses against both components of a combination Gag and Env vaccine. These data demonstrate the utility of the electroporation technology for use in large animals.
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