Mild iodine deficiency in fetal/neonatal life and neuropsychological performances
- PMID: 1519455
Mild iodine deficiency in fetal/neonatal life and neuropsychological performances
Abstract
The effects of mild/moderate iodine deficiency during the fetal/neonatal life on neuropsychological performances are still poorly defined. In this research we analyzed some parameters of cognitive performance with sensitive psychometric tests in children living in an area with moderate iodine deficiency. Each subject was submitted to the following neuropsychological tests: 1) a reaction time (RT) session, 2) the block design subtest of the WISC-R, 3) the coding subtest of the WISC-R. No significant difference was found between children with mild iodine deficiency and controls, for block design and coding tests. On the other hand controls had significantly faster RTs. Our data show that exposure to mild iodine deficiency in fetal/neonatal life does not affect general cognitive performance but influences the velocity of motor response to visual stimuli, which may be due to an alteration of the efficiency of the information processing mechanism.
Similar articles
-
[The prevention of disorders due to iodine deficiency: the experience of neuropsychological screening].Ann Ist Super Sanita. 1994;30(3):347-51. Ann Ist Super Sanita. 1994. PMID: 7533488 Italian.
-
Mild iodine deficiency during fetal/neonatal life and neuropsychological impairment in Tuscany.J Endocrinol Invest. 1995 Jan;18(1):57-62. doi: 10.1007/BF03349700. J Endocrinol Invest. 1995. PMID: 7759786
-
[Transient congenital hypothyroidism: physiopathology and clinica].Ann Ist Super Sanita. 1998;34(3):321-9. Ann Ist Super Sanita. 1998. PMID: 10052169 Review. Italian.
-
Congenital hypothyroidism and iodine status in Turkey: a comparison between the data obtained from an epidemiological study in school-aged children and neonatal screening for congenital hypothyroidism in Turkey.Pediatr Endocrinol Rev. 2003 Dec;1 Suppl 2:155-61. Pediatr Endocrinol Rev. 2003. PMID: 16444153
-
[Transient neonatal hypothyroidism and iodine deficiency].Ann Ist Super Sanita. 1994;30(3):309-16. Ann Ist Super Sanita. 1994. PMID: 7879997 Review. Italian.
Cited by
-
Hormones and cognition: current concepts and issues in neuropsychology.Neuropsychol Rev. 1999 Dec;9(4):175-207. doi: 10.1023/a:1021634622577. Neuropsychol Rev. 1999. PMID: 10667447 Review.
-
Controversies in urinary iodine determinations.Clin Biochem. 2002 Nov;35(8):575-9. doi: 10.1016/s0009-9120(02)00406-x. Clin Biochem. 2002. PMID: 12498990 Free PMC article. Review.
-
Iodine Intake and Related Cognitive Function Impairments in Elementary Schoolchildren.Biology (Basel). 2022 Oct 14;11(10):1507. doi: 10.3390/biology11101507. Biology (Basel). 2022. PMID: 36290411 Free PMC article.
-
Iodine supplementation for women during the preconception, pregnancy and postpartum period.Cochrane Database Syst Rev. 2017 Mar 5;3(3):CD011761. doi: 10.1002/14651858.CD011761.pub2. Cochrane Database Syst Rev. 2017. PMID: 28260263 Free PMC article.
-
Reduced hippocampal brain-derived neurotrophic factor (BDNF) in neonatal rats after prenatal exposure to propylthiouracil (PTU).Endocrinology. 2012 Mar;153(3):1311-6. doi: 10.1210/en.2011-1437. Epub 2012 Jan 17. Endocrinology. 2012. PMID: 22253429 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources