Review
[Effect of gene dose in human cells]
[Article in
Russian]
- PMID: 151956
Item in Clipboard
Review
[Effect of gene dose in human cells]
[Article in
Russian]
Tsitol Genet.
1978 Jul-Aug.
Abstract
Data from literature are reviewed on the gene dosage effect in human cells. Until recently the dosage effects have been distinctly shown for the genes of superoxide dismutase-1, acid phosphatase of erythrocytes, adenine phosphoribosyl transferase, glutathione reductase and nucleoside phosphorylase, located on chromosomes 21, 2, 16, 8, 14, respectively. The data are discussed in the light of problems arising from the study of the regulation of gene expression in man.
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