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Review
. 1992 May 1;202(2):215-38.
doi: 10.1016/0003-2697(92)90099-s.

Enzyme-catalyzed oligosaccharide synthesis

Affiliations
Review

Enzyme-catalyzed oligosaccharide synthesis

Y Ichikawa et al. Anal Biochem. .

Abstract

Cell-surface carbohydrates and their conjugates are involved in many types of molecular recognition. This review describes recent developments in enzyme-catalyzed oligosaccharide synthesis, with particular focus on glycosyltransferase and glycosidase reactions. With the increasing availability of glycosyltransferases via recombinant DNA technology, glycosyltransferase-catalyzed glycosylation with in situ regeneration of sugar nucleotides appears to be the most effective method for large-scale stereocontrolled oligosaccharide synthesis.

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