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Case Reports
. 2004 May;10(5):953-5.
doi: 10.3201/eid1005.030908.

Human and porcine hepatitis E virus strains, United Kingdom

Malcolm Banks  1 , Richard Bendall, Sylvia Grierson, Graham Heath, Jonathon Mitchell, Harry Dalton
Affiliations
Case Reports

Human and porcine hepatitis E virus strains, United Kingdom

Malcolm Banks et al. Emerg Infect Dis. 2004 May.

Abstract

We describe a case of acquired infection of a strain of hepatitis E virus (HEV) with a 100% amino acid identity to the analogous region in strains of HEV circulating in a United Kingdom pig herd. This case further supports the theory that autochthonous HEV infection in industrialized countries is zoonotic.

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Figures

Figure 1
Figure 1
Outline of dendrogram of selected partial nucleotide sequences of ORF-2 region of swine and human hepatitis E virus (HEV) isolates (300 nt). Avian hepatitis E virus (AY043166) was chosen as an outgroup for these analyses. Genotypic groupings are indicated. Clustering of the human UK HEV isolate and closely related sequences is highlighted within shaded area (Figure 2).
Figure 2
Figure 2
Human United Kingdom isolate (AY362357) is shown in bold and compared with closely related swine and human hepatitis E virus isolates (GenBank accession no., country of origin, and host are indicated). Bootstrap values greater than 70% are considered significant and are indicated.
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