Human challenge pilot study with Cyclospora cayetanensis
- PMID: 15200870
- PMCID: PMC3323087
- DOI: 10.3201/eid1004.030356
Human challenge pilot study with Cyclospora cayetanensis
Abstract
We describe a pilot study that attempted to infect human volunteers with Cyclospora cayetanensis. Seven healthy volunteers ingested an inoculum of Cyclospora oocysts (approximately 200-49,000 oocysts). The volunteers did not experience symptoms of gastroenteritis, and no oocysts were detected in any stool samples during the 16 weeks volunteers were monitored.
References
-
- Upton SJ. In vitro cultivation of Cryptosporidium. In: Fayer R, editor. Cryptosporidiosis of man and animals. 2nd ed. Boca Raton (FL): CRC Press; 1997. p. 181–207.
-
- Ash RA, Orihel TC. Parasites: a guide to laboratory procedures and identification. Chicago: ASCP Press; 1991.
-
- Eberhard ML, Pieniazek NJ, Arrowood MJ. Laboratory diagnosis of Cyclospora infections. Arch Pathol Lab Med. 1997;121:792–7. - PubMed
-
- Eberhard ML, Ortega YR, Haynes DE, Nace EK, Do RQ, Robi MG, et al. Attempts to establish experimental Cyclospora cayetanensis infection in laboratory animals. J Parasitol. 2000;86:577–82. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources