Sixteen cases of sclerosing hemangioma of the lung including unusual presentations
- PMID: 15201499
- PMCID: PMC2816834
- DOI: 10.3346/jkms.2004.19.3.352
Sixteen cases of sclerosing hemangioma of the lung including unusual presentations
Abstract
Sclerosing hemangiomas (SH) of the lung are uncommon tumors and are thought to be benign. However, the biologic behavior of this tumor has not yet been characterized adequately. The clinicopathologic features were reviewed and analyzed for 16 cases of SH. The age of the patients ranged from 37 to 73 yr (mean 50.6 yr). There were fifteen female and one male patient. The SH located at the intraparenchyme in 14 cases, the interlobar fissure in one case and the visceral pleura in one case. The size of SH ranged from 0.3 cm to 8 cm (mean 2.6 cm). There were five unusual presentations of SH including a case having two SH with multiple nodules of atypical adenomatous hyperplasia in the same lobe, a case showing adenocarcinoma-like area within the SH, a case showing one peribronchial lymph node metastasis (N1 nodal stage) with location of interlobar major fissure, a case showing alveolar adenoma-like area within the SH, and one case with a large visceral pleural-based pedunculated mass presenting as mediastinal mass. All patients were alive and well without recurrence at the last follow up. Here, we reviewed previously published literatures and discussed the histogenesis of SH.
Figures


Similar articles
-
Sclerosing hemangioma with lymph nodal metastases.Indian J Pathol Microbiol. 2009 Jul-Sep;52(3):392-4. doi: 10.4103/0377-4929.55004. Indian J Pathol Microbiol. 2009. PMID: 19679971
-
Sclerosing hemangioma with lymph node metastasis.Yonsei Med J. 2003 Feb;44(1):150-4. doi: 10.3349/ymj.2003.44.1.150. Yonsei Med J. 2003. PMID: 12619190
-
Pulmonary sclerosing hemangioma with lymph node metastases: report of 4 cases.Arch Pathol Lab Med. 2003 Mar;127(3):321-5. doi: 10.5858/2003-127-0321-PSHWLN. Arch Pathol Lab Med. 2003. PMID: 12653576
-
Lung tumors of uncertain histogenesis.Semin Diagn Pathol. 1995 May;12(2):185-92. Semin Diagn Pathol. 1995. PMID: 7638450 Review.
-
Sclerosing hemangioma of the lung: a clinicopathologic study.Zhonghua Yi Xue Za Zhi (Taipei). 1993 Sep;52(3):149-54. Zhonghua Yi Xue Za Zhi (Taipei). 1993. PMID: 8252456 Review.
Cited by
-
[Diagnosis and treatment for pulmonary sclerosing hemangioma].Zhongguo Fei Ai Za Zhi. 2011 Aug;14(8):674-8. doi: 10.3779/j.issn.1009-3419.2011.08.07. Zhongguo Fei Ai Za Zhi. 2011. PMID: 21859549 Free PMC article. Chinese.
-
Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case.World J Surg Oncol. 2011 Jun 6;9:62. doi: 10.1186/1477-7819-9-62. World J Surg Oncol. 2011. PMID: 21645337 Free PMC article.
-
A rare case of pulmonary sclerosing hemagioma with lymph node metastasis and review of the literature.Int J Clin Exp Pathol. 2015 Jul 1;8(7):8619-23. eCollection 2015. Int J Clin Exp Pathol. 2015. PMID: 26339444 Free PMC article. Review.
-
Sclerosing hemangioma of the lung showing strong FDG avidity on PET scan: Case report and review of the current literature.Respir Med Case Rep. 2015 Dec 20;17:20-3. doi: 10.1016/j.rmcr.2015.12.005. eCollection 2016. Respir Med Case Rep. 2015. PMID: 27222778 Free PMC article.
-
Multiple peripheral typical carcinoid tumors of the lung: associated with sclerosing hemangiomas.Diagn Pathol. 2013 Jun 17;8:97. doi: 10.1186/1746-1596-8-97. Diagn Pathol. 2013. PMID: 23773456 Free PMC article.
References
-
- Liebow AA, Hubbell DS. Sclerosing hemangioma (histiocytoma, xanthoma) of the lung. Cancer. 1956;9:53–75. - PubMed
-
- Huszar M, Suster S, Herczeg E, Geiger B. Sclerosing hemangioma of the lung. Immunohistochemical demonstration of mesenchymal origin using antibodies to tissue-specific intermediate filaments. Cancer. 1986;58:2422–2427. - PubMed
-
- Katzenstein AL, Weise DL, Fulling K, Battifora H. So-called sclerosing hemangioma of the lung. Evidence for mesothelial origin. Am J Surg Pathol. 1983;7:3–14. - PubMed
-
- Xu HM, Li WH, Hou N, Zhang SG, Li HF, Wang SQ, Yu ZY, Li ZJ, Zeng MY, Zhu GM. Neuroendocrine differentiation in 32 cases of so-called sclerosing hemangioma of the lung: identified by immunohistochemical and ultrastructural study. Am J Surg Pathol. 1997;21:1013–1022. - PubMed
-
- Chan AC, Chan JK. Pulmonary sclerosing hemangioma consistently expresses thyroid transcription factor-1 (TTF-1): a new clue to its histogenesis. Am J Surg Pathol. 2000;24:1531–1536. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical