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Case Reports
. 2004 Jun;19(3):477-80.
doi: 10.3346/jkms.2004.19.3.477.

Giant cell malignant fibrous histiocytoma of the breast: a case report

Se Jeong Oh  1 , Kyoung Mee Kim, Tae Ho Hong, Woo Chan Park, Jeong Soo Kim, Sang Seol Jung
Affiliations
Case Reports

Giant cell malignant fibrous histiocytoma of the breast: a case report

Se Jeong Oh et al. J Korean Med Sci. 2004 Jun.

Abstract

A case of primary malignant fibrous histiocytoma of the breast is reported. The patient was a 48-yr-old woman with a huge tumor involving almost the entire left breast. The central portion of her left breast was already rotted by extensive necrosis and inflammation. She was treated by radical mastectomy and axillary lymphadenectomy to level I. Pathologic examination supported by an immunohistochemical staining confirmed the tumor as malignant fibrous histiocytoma of giant cell type. Axillary lymph nodes were free from tumor metastasis. She had not taken any postoperative adjuvant therapy. The metastasis to lungs was found 2 months after the operation, and she died within 6 months.

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Figures

Fig. 1
Fig. 1
Gross finding of the tumor. The tumor involves almost the entire left breast, which is rotted by extensive necrosis and inflammation.
Fig. 2
Fig. 2
Microscopic findings of the tumor. Low power (A, H&E, ×100) and high power (B, H&E, ×400) examinations show many multinucleated osteoclast-like giant cells and hyperchromatic mononuclear tumor cells.
See this image and copyright information in PMC

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