Involvement and role of the hypothalamo-pituitary-adrenal (HPA) stress axis in animal models of chronic pain and inflammation
- PMID: 15204028
- DOI: 10.1080/10253890310001650268
Involvement and role of the hypothalamo-pituitary-adrenal (HPA) stress axis in animal models of chronic pain and inflammation
Abstract
Hypothalamo-pituitary-adrenal (HPA) axis changes have been reported in several disease states, including major depressive disorder, rheumatoid arthritis, multiple sclerosis and various other conditions associated with chronic pain. These observations suggest that stress and the HPA axis may play important roles in the pathology of these diseases. In order to contribute to a better understanding of the role that chronic stress may play in human pathology, this review article explores the involvement of the HPA axis in those animal models of chronic pain and inflammation that entail persistent rather than intermittent stress.
Copyright 2004 Taylor and Francis Ltd.
Similar articles
-
Normal hypothalamo-pituitary-adrenal axis function in a rat model of peripheral neuropathic pain.Brain Res. 2005 May 24;1044(2):216-26. doi: 10.1016/j.brainres.2005.03.005. Epub 2005 Apr 13. Brain Res. 2005. PMID: 15885220
-
The hypothalamo-pituitary-adrenal axis in chronic fatigue syndrome and fibromyalgia syndrome.Stress. 2007 Mar;10(1):13-25. doi: 10.1080/10253890601130823. Stress. 2007. PMID: 17454963 Review.
-
Stress and hypothalamic-pituitary-adrenal axis function in experimental autoimmune encephalomyelitis and multiple sclerosis - a review.Psychoneuroendocrinology. 2007 Jul;32(6):604-18. doi: 10.1016/j.psyneuen.2007.05.002. Epub 2007 Jun 29. Psychoneuroendocrinology. 2007. PMID: 17602841 Review.
-
Limbic and HPA axis function in an animal model of chronic neuropathic pain.Physiol Behav. 2006 Jun 15;88(1-2):67-76. doi: 10.1016/j.physbeh.2006.03.012. Epub 2006 May 2. Physiol Behav. 2006. PMID: 16647726
-
The role of vasopressin in hypothalamo-pituitary-adrenal axis activation during stress: an assessment of the evidence.Ann N Y Acad Sci. 2004 Jun;1018:151-61. doi: 10.1196/annals.1296.018. Ann N Y Acad Sci. 2004. PMID: 15240364 Review.
Cited by
-
Increased extracellular water measured by bioimpedance and by increased serum levels of atrial natriuretic peptide in RA patients-signs of volume overload.Clin Rheumatol. 2017 May;36(5):1041-1051. doi: 10.1007/s10067-016-3286-x. Epub 2016 Apr 26. Clin Rheumatol. 2017. PMID: 27112146
-
High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity.Int J Neuropsychopharmacol. 2015 Sep 5;19(3):pyv095. doi: 10.1093/ijnp/pyv095. Int J Neuropsychopharmacol. 2015. PMID: 26342110 Free PMC article. Review.
-
The Link Between Stress and Endometriosis: from Animal Models to the Clinical Scenario.Reprod Sci. 2020 Sep;27(9):1675-1686. doi: 10.1007/s43032-020-00205-7. Epub 2020 Jun 15. Reprod Sci. 2020. PMID: 32542543 Free PMC article. Review.
-
Restless legs syndrome in patients with irritable bowel syndrome: response to small intestinal bacterial overgrowth therapy.Dig Dis Sci. 2008 May;53(5):1252-6. doi: 10.1007/s10620-007-0021-0. Epub 2007 Oct 13. Dig Dis Sci. 2008. PMID: 17934858
-
Corticotropin-Releasing Factor Mediates Pain-Induced Anxiety through the ERK1/2 Signaling Cascade in Locus Coeruleus Neurons.Int J Neuropsychopharmacol. 2015 Feb 25;18(8):pyv019. doi: 10.1093/ijnp/pyv019. Int J Neuropsychopharmacol. 2015. PMID: 25716783 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical