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Case Reports
. 2004 Jul 1;39(1):129-32.
doi: 10.1086/421386. Epub 2004 Jun 1.

Immune reconstitution hepatitis in HIV and hepatitis B coinfection, despite lamivudine therapy as part of HAART

Anne Drake  1 , Anne Mijch, Joe Sasadeusz
Affiliations
Case Reports

Immune reconstitution hepatitis in HIV and hepatitis B coinfection, despite lamivudine therapy as part of HAART

Anne Drake et al. Clin Infect Dis. .

Abstract

Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) coinfection occurs commonly. The introduction of antiretroviral therapy can result in immune reconstitution hepatitis. We describe 2 coinfected patients who developed clinical flares of HBV disease, despite the inclusion of lamivudine, a drug with anti-HBV activity, in their HAART regimens. Potential strategies to manage individuals with HBV/HIV coinfection are discussed.

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