[Pulse wave velocity(PWV)]

Abstract

Brachial-ankle pulse wave velocity(baPWV) is a noninvasive and simple method of measuring arterial stiffness and an independent predictor of cardiovascular mortality in some lifestyle-related diseases. We evaluated that baPWV is well correlated with many atherosclerotic risk factors including abdominal visceral obesity and HOMA, and that the accumulation of these risk factors increases baPWV. The promotion of exercise and nutrition education for metabolic syndrome patients improves not only each risk factor but also baPWV. Multiple linear regression analysis demonstrated that baPWV is improved by decreases in SBP and BMI through several lifestyle modifications. Reversibility of baPWV suggests that vessel damage is not so serious and may be only endothelial dysfunction. Therefore baPWV should be monitored and ameliorated in treating metabolic syndrome.