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. 2004 Jun;10(6):1134-7.
doi: 10.3201/eid1006.030472.

Bacteriophages and diffusion of beta-lactamase genes

Maite Muniesa  1 , Aurora García, Elisenda Miró, Beatriz Mirelis, Guillem Prats, Juan Jofre, Ferran Navarro
Affiliations

Bacteriophages and diffusion of beta-lactamase genes

Maite Muniesa et al. Emerg Infect Dis. 2004 Jun.

Abstract

We evaluated the presence of various Beta-lactamase genes within the bacteriophages in sewage. Results showed the occurrence of phage particles carrying sequences of bla(OXA-2), bla(PSE-1) or bla(PSE-4) and bla(PSE)-type genes. Phages may contribute to the spread of some Beta-lactamase genes.

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Figures

Figure
Figure
Deduced amino acid sequence of PSE-1 (A), and OXA-2 (B) related enzymes that could be detected by polymerase chain reaction. Amino acids in boldface correspond to the regions of the primers. Dots indicate identical amino acids, and dashes indicate omitted regions with identical amino acids. Numbers correspond to amino acid position. Sequences obtained are underlined. GenBank accession no. of sequences: PSE-1: Q03170, PSE-4: P16897, PSE-5: AAG23870, CARB-3: P37322, CARB-8: AAM92465, Proteus pCS229 blaP: JS0755, OXA-2: CAA30246, OXA-3: AAC41449, OXA-15: AAB05874, OXA-21: CAA71699, and OXA-32: AAK58418.
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