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. 2004 Jul 19;91(2):205-7.
doi: 10.1038/sj.bjc.6601886.

The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases

R Al-Shaiba  1 , D C McMillan, W J Angerson, E Leen, C S McArdle, P Horgan
Affiliations

The relationship between hypoalbuminaemia, tumour volume and the systemic inflammatory response in patients with colorectal liver metastases

R Al-Shaiba et al. Br J Cancer. .

Abstract

The relationship between hypoalbuminaemia, tumour volume and C-reactive protein was examined in patients with colorectal liver metastases (n=57). On multiple regression analysis, albumin concentrations were independently associated with C-reactive protein (r=0.56, P<0.001) but not percentage hepatic replacement (P=0.34). These results show that hypoalbuminaemia is associated with the presence of a systemic inflammatory response rather than tumour volume in patients with colorectal liver metastases.

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Figures

Figure 1
Figure 1
The relationship between albumin and C-reactive protein concentrations in patients with colorectal liver metastases (n=57).
See this image and copyright information in PMC

References

    1. Dixon MR, Haukoos JS, Udani SM, Naghi JJ, Arnell TD, Kumar RR, Stamos MJ (2003) Carcinoembryonic antigen and albumin predict survival in patients with advanced colon and rectal cancer. Arch Surg 138: 962–966 - PubMed
    1. Dworkin MJ, Burke D, Earlam S, Fordy C, Allen-Mersh TG (1995) Measurement of response to treatment in colorectal liver metastases. Br J Cancer 71: 873–876 - PMC - PubMed
    1. Forrest LM, McMillan DC, McArdle CS, Angerson WJ, Dunlop DJ (2003) Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer 89: 1028–1030 - PMC - PubMed
    1. Franch-Arcas G (2001) The meaning of hypoalbuminaemia in clinical practice. Clin Nutr 20: 265–269 - PubMed
    1. McMillan DC, Watson WS, O'Gorman P, Preston T, Scott HR, McArdle CS (2001) Albumin concentrations are primarily determined by the body cell mass and the systemic inflammatory response in cancer patients with weight loss. Nutr Cancer 39: 210–213 - PubMed