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Review
. 1992 Sep;12(3):449-61.

Linkage analysis and predicting genetic disease

J A Boughman  1 , M J Stick, D A Peterson, M M Cohen
Affiliations
  • PMID: 1521423
Review

Linkage analysis and predicting genetic disease

J A Boughman et al. Clin Lab Med. 1992 Sep.

Abstract

Linkage analysis is an important and clinically applicable method of predicting risk for genetic disorders and traits. When a gene cannot be detected directly, evaluation of a closely linked marker may be used in risk assessment. This review of linkage analysis provides basic information and examples of the application of these methods in genetic counseling situations.

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