Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004;6(4):151-4.
doi: 10.1186/ar1196. Epub 2004 Jun 4.

What should be the core outcomes in chronic pain clinical trials?

Dennis C Turk  1 , Robert H Dworkin
Affiliations
Review

What should be the core outcomes in chronic pain clinical trials?

Dennis C Turk et al. Arthritis Res Ther. 2004.

Abstract

A consensus conference with representatives from academia, governmental agencies, and the pharmaceutical industry met and concluded that clinical trials designed to assess the efficacy and effectiveness of treatments for chronic pain should consider outcomes in six core domains: pain, physical functioning, emotional functioning, patient global ratings of satisfaction, negative health states and adverse events, and patient disposition. In addition, it was acknowledged that there are many secondary domains that might be of importance and should be included in trials depending on the nature of the treatment and population to whom the treatment is targeted.

PubMed Disclaimer

References

    1. Abbott FV, Fraser MI. Use and abuse of over-the-counter analgesic agents. J Psychiat Neurosci. 1998;23:13–34. - PMC - PubMed
    1. Pleis JR, Coles R. Summary health statistics for US adults: National Health Interview Survey, 1998. 209. Vol. 10. National Center for Health Statistics, Vital Health Statistics; 2002. - PubMed
    1. United States Bureau of the Census . Statistical Abstract of the United States: 1996. 116. Washington DC: US Bureau of the Census; 1996.
    1. National Research Council . Musculoskeletal disorders and the workplace. Washington DC: National Academy Press; 2001.
    1. Deyo RA, Battie M, Beurskens AHHM, Bombardier C, Croft P, Koes B. Outcome measures for low back pain research. A proposal for standardized use. Spine. 1998;23:2003–2013. doi: 10.1097/00007632-199809150-00018. - DOI - PubMed

Publication types