Review
doi: 10.1016/j.molcel.2004.06.031.
Regulation of mRNA decay: decapping goes solo
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- PMID: 15225542
- DOI: 10.1016/j.molcel.2004.06.031
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Review
Regulation of mRNA decay: decapping goes solo
Mol Cell.
.
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Abstract
In this issue of Molecular Cell, Badis et al. demonstrate that autoregulated destabilization of the RPS28B mRNA is mediated by Edc3p interaction with an Rps28p/3'UTR mRNP complex. Subsequent recruitment of Dcp1p/Dcp2p to the complex appears to ensure rapid, deadenylation-independent decapping of the mRNA.
Comment on
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Targeted mRNA degradation by deadenylation-independent decapping.Mol Cell. 2004 Jul 2;15(1):5-15. doi: 10.1016/j.molcel.2004.06.028. Mol Cell. 2004. PMID: 15225544
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