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. 2004 Aug 2;14(15):3953-6.
doi: 10.1016/j.bmcl.2004.05.053.

Oxamides as novel NR2B selective NMDA receptor antagonists

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Oxamides as novel NR2B selective NMDA receptor antagonists

Gizella Barta-Szalai et al. Bioorg Med Chem Lett. .

Abstract

A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.

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