Oxamides as novel NR2B selective NMDA receptor antagonists
- PMID: 15225705
- DOI: 10.1016/j.bmcl.2004.05.053
Oxamides as novel NR2B selective NMDA receptor antagonists
Abstract
A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test.
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