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Review
. 2004 Jul;7(1):5-6.
doi: 10.1016/j.devcel.2004.06.011.

Thirteen is the lucky number for doublecortin

Anna Akhmanova  1 , Fedor Severin
Affiliations
Free article
Review

Thirteen is the lucky number for doublecortin

Anna Akhmanova et al. Dev Cell. 2004 Jul.
Free article

Abstract

Doublecortin is a microtubule-associated protein that is essential for normal brain development. A recent report published in Molecular Cell shows that doublecortin associates preferentially with microtubules made of 13 protofilaments, by recognizing a novel site between the protofilaments. These findings explain how doublecortin stabilizes microtubules and provide clues about its function during neuronal migration.

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