Actin cytoskeleton: formins lead the way
- PMID: 15242634
- DOI: 10.1016/j.cub.2004.06.043
Actin cytoskeleton: formins lead the way
Abstract
Formins are eukaryotic proteins that potently influence actin polymerization dynamics. Recent evidence strongly suggests that these proteins move processively with the elongating barbed ends of actin filaments.
Similar articles
-
Drosophila and human FHOD family formin proteins nucleate actin filaments.J Biol Chem. 2018 Jan 12;293(2):532-540. doi: 10.1074/jbc.M117.800888. Epub 2017 Nov 10. J Biol Chem. 2018. PMID: 29127202 Free PMC article.
-
Direct observation of the conformational states of formin mDia1 at actin filament barbed ends and along the filament.Mol Biol Cell. 2023 Jan 1;34(1):ar2. doi: 10.1091/mbc.E22-10-0472. Epub 2022 Nov 16. Mol Biol Cell. 2023. PMID: 36383775 Free PMC article.
-
Role of formins in actin assembly: nucleation and barbed-end association.Science. 2002 Jul 26;297(5581):612-5. doi: 10.1126/science.1072309. Epub 2002 Jun 6. Science. 2002. PMID: 12052901
-
Origins and evolution of the actin cytoskeleton.Adv Exp Med Biol. 2007;607:97-110. doi: 10.1007/978-0-387-74021-8_8. Adv Exp Med Biol. 2007. PMID: 17977462 Review. No abstract available.
-
Fifteen formins for an actin filament: a molecular view on the regulation of human formins.Biochim Biophys Acta. 2010 Feb;1803(2):152-63. doi: 10.1016/j.bbamcr.2010.01.014. Epub 2010 Jan 25. Biochim Biophys Acta. 2010. PMID: 20102729 Review.
Cited by
-
Central roles of small GTPases in the development of cell polarity in yeast and beyond.Microbiol Mol Biol Rev. 2007 Mar;71(1):48-96. doi: 10.1128/MMBR.00028-06. Microbiol Mol Biol Rev. 2007. PMID: 17347519 Free PMC article. Review.
-
Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease.Neural Plast. 2016;2016:2371970. doi: 10.1155/2016/2371970. Epub 2016 Apr 5. Neural Plast. 2016. PMID: 27127658 Free PMC article. Review.
-
WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells.J Cell Biol. 2008 Mar 24;180(6):1245-60. doi: 10.1083/jcb.200708123. J Cell Biol. 2008. PMID: 18362183 Free PMC article.
-
Actin Out: Regulation of the Synaptic Cytoskeleton.J Biol Chem. 2015 Nov 27;290(48):28613-22. doi: 10.1074/jbc.R115.655118. Epub 2015 Oct 9. J Biol Chem. 2015. PMID: 26453304 Free PMC article. Review.
-
The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages.Infect Immun. 2013 May;81(5):1683-95. doi: 10.1128/IAI.01411-12. Epub 2013 Mar 4. Infect Immun. 2013. PMID: 23460512 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources