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Clinical Trial
. 2004 Jul 31;329(7460):258.
doi: 10.1136/bmj.38156.767118.7C. Epub 2004 Jul 8.

Randomised controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimisation of circulatory status after cardiac surgery

Moira McKendry  1 , Helen McGloin, Debbie Saberi, Libby Caudwell, Anthony R Brady, Mervyn Singer
Affiliations
Clinical Trial

Randomised controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimisation of circulatory status after cardiac surgery

Moira McKendry et al. BMJ. .

Erratum in

  • BMJ. 2004 Aug 21;329(7463):438

Abstract

Objective: To assess whether a nurse led, flow monitored protocol for optimising circulatory status in patients after cardiac surgery reduces complications and shortens stay in intensive care and hospital.

Design: Randomised controlled trial.

Setting: Intensive care unit and cardiothoracic unit of a university teaching hospital.

Participants: 174 patients who underwent cardiac surgery between April 2000 and January 2003.

Interventions: Patients were allocated to conventional haemodynamic management or to an algorithm guided by oesophageal Doppler flowmetry to maintain a stroke index above 35 ml/m2.

Results: 26 control patients had postoperative complications (two deaths) compared with 17 (four deaths) protocol patients (P = 0.08). Duration of hospital stay in the protocol group was significantly reduced from a median of nine (interquartile range 7-12) days to seven (7-10) days (P = 0.02). The mean duration of hospital stay was reduced from 13.9 to 11.4 days, a saving in hospital bed days of 18% (95% confidence interval -12% to 47%). Usage of intensive care beds was reduced by 23% (-8% to 59%).

Conclusion: A nurse delivered protocol for optimising circulatory status in the early postoperative period after cardiac surgery may significantly shorten hospital stay.

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Figures

Fig 1
Fig 1
Treatment algorithm to optimise circulatory status in patients after cardiac surgery
Fig 2
Fig 2
Flow of participants through trial
Fig 3
Fig 3
Duration of stay in intensive care and hospital in patients receiving strategy to optimise circulatory status after cardiac surgery (protocol) or conventional management (control). Six hospital stays beyond 50 days not shown
See this image and copyright information in PMC

Comment in

References

    1. Shoemaker WC, Wo CC, Thangathurai D, Velmahos G, Belzberg H, Asensio JA, et al. Haemodynamic patterns of survivors and non survivors during high risk elective surgical operations. World J Surg 1999;23: 1264-70. - PubMed
    1. Kern JW, Shoemaker WC. Meta analysis of hemodynamic optimisation in high risk patients. Crit Care Med 2002;30: 1686-9. - PubMed
    1. Sandham JD, Hull RD, Brant RF, Knox L, Pineo GF, Doig CJ, et al. A randomised, controlled trial of the use of pulmonary artery catheters in high risk surgical patients. N Engl J Med 2003;348: 5-14. - PubMed
    1. Polonen P, Ruokonen E, Hippelainem M, Poyhonen M, Takala J. A prospective randomised study of goal oriented hemodynamic therapy in cardiac surgical patients. Anaesth Analg 2000;90: 1052-9. - PubMed
    1. Poeze M, Ramsay G, Greve JWM, Singer M. Prediction of post operative cardiac surgical morbidity and organ failure within 4 hours of ICU admission using esophageal Doppler ultrasonography. Crit Care Med 1999;27: 1288-94. - PubMed

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