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Comparative Study
. 2004 Jul;11(4):792-4.
doi: 10.1128/CDLI.11.4.792-794.2004.

Kinetics of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in 271 laboratory-confirmed cases of SARS

Zhongping He  1 , Qingming Dong, Hui Zhuang, Shujing Song, Guoai Peng, Guangxiang Luo, Dominic E Dwyer
Affiliations
Comparative Study

Kinetics of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in 271 laboratory-confirmed cases of SARS

Zhongping He et al. Clin Diagn Lab Immunol. 2004 Jul.

Abstract

The sensitivities and specificities of an immunofluorescence assay and an enzyme immunoassay for detection of antibodies specific for severe acute respiratory syndrome coronavirus (SARS-CoV) were compared for 148 laboratory-confirmed SARS cases. The appearance and persistence of SARS-CoV-specific antibodies were assessed, with immunoglobulin G detected in 59% of samples collected within 14 days and persisting for 60 to 95 days after the onset of illness.

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