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. 2004 Aug 1;12(15):3971-6.
doi: 10.1016/j.bmc.2004.06.010.

(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals

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(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals

Saeed Emami et al. Bioorg Med Chem. .

Abstract

A series of 1,2,4-triazolylchromanone oxime ethers were synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger and Microsporum gypseum.

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