(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals
- PMID: 15246073
- DOI: 10.1016/j.bmc.2004.06.010
(E)- and (Z)-1,2,4-triazolylchromanone oxime ethers as conformationally constrained antifungals
Abstract
A series of 1,2,4-triazolylchromanone oxime ethers were synthesized and tested for in vitro antifungal activity. Many of these derivatives exhibit high activity against Candida albicans, Saccharomyces cerevisiae, Aspergillus niger and Microsporum gypseum.
Similar articles
-
Stereoselective synthesis and in vitro antifungal evaluation of (E)- and (Z)-imidazolylchromanone oxime ethers.Arch Pharm (Weinheim). 2002 Jul;335(7):318-24. doi: 10.1002/1521-4184(200209)335:7<318::AID-ARDP318>3.0.CO;2-O. Arch Pharm (Weinheim). 2002. PMID: 12207281
-
Stereoselective synthesis and antifungal activity of (Z)-trans-3-azolyl-2-methylchromanone oxime ethers.Bioorg Med Chem. 2004 Nov 15;12(22):5881-9. doi: 10.1016/j.bmc.2004.08.030. Bioorg Med Chem. 2004. PMID: 15498664
-
Oxime and oxime ether derivatives of 1,4-benzothiazine related to oxiconazole.ChemMedChem. 2007 Aug;2(8):1208-13. doi: 10.1002/cmdc.200700066. ChemMedChem. 2007. PMID: 17541993
-
DNA topoisomerase inhibitors as antifungal agents.Adv Pharmacol. 1994;29B:227-44. doi: 10.1016/s1054-3589(08)61140-0. Adv Pharmacol. 1994. PMID: 8996610 Review. No abstract available.
-
Chemistry of six-membered cyclic oxime ethers. Application in the synthesis of bioactive compounds.Chem Rev. 2011 Aug 10;111(8):5004-41. doi: 10.1021/cr100292w. Epub 2011 Mar 24. Chem Rev. 2011. PMID: 21434602 Review. No abstract available.
Cited by
-
1-(1-Benzofuran-2-yl)ethanone O-(4-chloro-benz-yl)oxime.Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3178. doi: 10.1107/S1600536812042675. Epub 2012 Oct 20. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 23284491 Free PMC article.
-
Synthesis and Biological Activity of Novel O-Alkyl Derivatives of Naringenin and Their Oximes.Molecules. 2017 Sep 6;22(9):1485. doi: 10.3390/molecules22091485. Molecules. 2017. PMID: 28878189 Free PMC article.
-
Synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones.Daru. 2012 Oct 4;20(1):46. doi: 10.1186/2008-2231-20-46. Daru. 2012. PMID: 23351328 Free PMC article.
-
Novel triazole alcohol antifungals derived from fluconazole: design, synthesis, and biological activity.Mol Divers. 2015 Feb;19(1):15-27. doi: 10.1007/s11030-014-9548-0. Epub 2014 Sep 3. Mol Divers. 2015. PMID: 25182365
-
A Review of Biologically Active Oxime Ethers.Molecules. 2023 Jun 28;28(13):5041. doi: 10.3390/molecules28135041. Molecules. 2023. PMID: 37446703 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases