Vaccination and allergic disease: a birth cohort study
- PMID: 15249303
- PMCID: PMC1448377
- DOI: 10.2105/ajph.94.6.985
Vaccination and allergic disease: a birth cohort study
Abstract
Objectives: We examined the effect of vaccination for diphtheria; polio; pertussis and tetanus; or measles, mumps, and rubella on the incidence of physician-diagnosed asthma and eczema.
Methods: We used a previously established birth cohort in the West Midlands General Practice research database.
Results: We found an association between vaccination and the development of allergic disease; however, this association was present only among children with the fewest physician visits and can be explained by this factor.
Conclusions: Our data suggest that currently recommended routine vaccinations are not a risk factor for asthma or eczema.
Comment in
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Vaccination and risk of allergic disease.Am J Public Health. 2005 Jan;95(1):6; author reply 6-7. doi: 10.2105/AJPH.2004.050583. Am J Public Health. 2005. PMID: 15623850 Free PMC article. No abstract available.
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References
-
- Chadwick DJ, Cardew G. The Rising Trends in Asthma. Chichester, England: John Wiley & Sons; 1997.
-
- Sen DK, Arora S, Gupta S, Sanyal RK. Studies of adrenergic mechanisms in relation to histamine sensitivity in children immunized with Bordetella pertussis vaccine. J Allergy Clin Immunol. 1974;54:25–31. - PubMed
-
- Odelram H, Granstrom M, Hedenskog S, Duchen K, Bjorksten B. Immunoglobulin E and G responses to pertussis toxin after booster immunization in relation to atopy, local reactions and aluminium content of the vaccines. Pediatr Allergy Immunol. 1994; 5:118–123. - PubMed