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Comparative Study
. 1992 May;33(5):517-20.
doi: 10.1111/j.1365-2125.1992.tb04081.x.

In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum

L K Basco  1 , C Gillotin, F Gimenez, R Farinotti, J Le Bras
Affiliations
Comparative Study

In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum

L K Basco et al. Br J Clin Pharmacol. 1992 May.

Abstract

The in vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline was compared against chloroquine-resistant and -susceptible strains of Plasmodium falciparum using a semi-micro drug susceptibility test. For each strain, the corresponding enantiomers exhibited similar activities. The enantiomers of halofantrine were the most active against both susceptible and resistant strains, followed by the enantiomers of mefloquine and enpiroline.

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References

    1. Science. 1976 Aug 20;193(4254):673-5 - PubMed
    1. Antimicrob Agents Chemother. 1989 Jul;33(7):1081-9 - PubMed
    1. J Med Chem. 1974 Feb;17(2):210-9 - PubMed
    1. Br J Clin Pharmacol. 1986 Jul;22(1):93-6 - PubMed
    1. J Med Chem. 1978 Apr;21(4):326-30 - PubMed

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