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. 2004 Jul 21;2(14):1965-6.
doi: 10.1039/b408001g. Epub 2004 Jun 22.

A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

M Eugenio Vazquez  1 , Deborah M Rothman, Barbara Imperiali
Affiliations

A new environment-sensitive fluorescent amino acid for Fmoc-based solid phase peptide synthesis

M Eugenio Vazquez et al. Org Biomol Chem. .

Abstract

A new 4-(N,N-dimethylamino) phthalimide-based environment-sensitive fluorescent building block for solid phase peptide synthesis, has been synthesized and incorporated into peptides. Peptides incorporating this residue show great potential for biological applications in sensing protein/protein interactions.

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