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Case Reports
. 2004 Jul;19(7):836-838.
doi: 10.1002/mds.20086.

Vascular hemichorea/hemiballism and topiramate

Emilia Mabel Gatto  1 , Claudia Uribe Roca  1 , Gabriela Raina  1 , Marcelo Gorja  1 , Silvia Folgar  1 , Federico E Micheli  1
Affiliations
Case Reports

Vascular hemichorea/hemiballism and topiramate

Emilia Mabel Gatto et al. Mov Disord. 2004 Jul.

Abstract

Although vascular hemichorea/hemiballism (HC/HB) has been reported to be self-limited, in some cases, it can be irreversible and severely disabling. The standard treatment includes typical and atypical neuroleptics and GABA-mimetic drugs. Topiramate is a new antiepileptic drug possessing a complex mechanism of action, including the enhancement of GABA-mediated inhibition. We describe a 71-year-old patient with HC/HB who markedly improved after topiramate treatment.

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