Review
doi: 10.1016/0959-4388(92)90177-m.
Second messenger signalling in olfaction
Affiliations
- PMID: 1525540
- DOI: 10.1016/0959-4388(92)90177-m
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Review
Second messenger signalling in olfaction
Curr Opin Neurobiol.
1992 Aug.
Abstract
The primary reactions of the chemo-electrical signal transduction pathway in olfactory receptor neurons are mediated by two alternative second messengers, cAMP and inositol 1,4,5-trisphosphate. The rapid and transient intracellular signalling is terminated by the action of negative-feedback loops which uncouple the reaction cascades (desensitization). Recent evidence suggests that secondary reactions in olfaction (adaptation) may also be controlled by second messengers.
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