[Potentiation of the effects of anxiolytics with magnesium salts]

Abstract

In a double blind trial the authors tested the assumption that magnesium potentiates by its specific action the therapeutic effect of anxiolytics. A group of 20 women treated on account of anxious depressive neurosis was divided into two sub-groups. The first was given anxiolytic and placebo, the second one anxiolytics and Mg-lactate in corresponding amounts. After 10 days the placebo and Mg-lactate were exchanged. Both groups were examined before treatment and then after 10 and 20 days of therapy by a series of psychological tests. It was revealed that the combination of anxiolytics and Mg-lactate leads to a more rapid reduction of psychopathological symptoms, in particular anxiety. In MAS and MHG tests the decline of anxiety was statistically significant at the level of p less than 0.05.