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Review
. 2004 Aug 15;223(1):25-7.
doi: 10.1016/j.jns.2004.04.015.

Mechanisms of mitoxantrone in multiple sclerosis--what is known?

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Review

Mechanisms of mitoxantrone in multiple sclerosis--what is known?

Oliver Neuhaus et al. J Neurol Sci. .

Abstract

The recent publication of the MIMS-study (Mitoxantrone In Multiple Sclerosis) and the approval of several health authorities support the use of mitoxantrone in patients with active relapsing-remitting or secondary progressive multiple sclerosis. This review provides information on data thus far present on the putative mechanisms of action of mitoxantrone in the immunopathogenesis of this disabling disease.

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