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Review
. 1992 Apr;24(2):181-91.
doi: 10.1007/BF00762676.

A unifying concept for ion translocation by retinal proteins

D Oesterhelt  1 , J Tittor, E Bamberg
Affiliations
Review

A unifying concept for ion translocation by retinal proteins

D Oesterhelt et al. J Bioenerg Biomembr. 1992 Apr.

Abstract

First, halorhodopsin is capable of pumping protons after illumination with green and blue light in the same direction as chloride. Second, mutated bacteriorhodopsin where the proton acceptor Asp85 and the proton donor Asp96 are replaced by Asn showed proton pump activity after illumination with blue light in the same direction as wildtype after green light illumination. These results can be explained by and are discussed in light of our new hypothesis: structural changes in either molecule lead to a change in ion affinity and accessibility for determining the vectoriality of the transport through the two proteins.

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References

    1. J Mol Biol. 1990 Jun 20;213(4):899-929 - PubMed
    1. Nature. 1980 Sep 25;287(5780):351-3 - PubMed
    1. FEBS Lett. 1976 Jun 1;65(2):175-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1989 Apr;86(7):2167-71 - PubMed
    1. EMBO J. 1985 Sep;4(9):2347-50 - PubMed