Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Aug;48(8):3179-81.
doi: 10.1128/AAC.48.8.3179-3181.2004.

Extended-spectrum-cephalosporin resistance in Salmonella enterica isolates of animal origin

Affiliations

Extended-spectrum-cephalosporin resistance in Salmonella enterica isolates of animal origin

Jeffrey T Gray et al. Antimicrob Agents Chemother. 2004 Aug.

Abstract

A total of 112 out of 5,709 Salmonella enterica isolates from domestic animal species exhibited decreased susceptibilities to ceftiofur and ceftriaxone, and each possessed the blaCMY gene. Ten Salmonella serotypes were significantly more likely to include resistant isolates. Isolates from turkeys, horses, cats, and dogs were significantly more likely to include resistant isolates.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Southern blot analysis of plasmid hybridization with PCR-amplified blacmy gene probes. Lane 1, supercoiled ladder; lane 2, positive control, S. enterica serotype Typhimurium, extended-spectrum-cephalosporin-resistant isolates; lane 3, S. enterica serotype Typhimurium 42/98; lane 4, S. enterica serotype Typhimurium-Copenhagen 4/97; lane 5, S. enterica serotype Typhimurium-Copenhagen 36/98; lane 6, S. enterica serotype Bredeney 72/98; lane 7, S. enterica serotype Heidelberg 61/98; lane 8, S. enterica serotype Newport 11/98; lane 9, S. enterica serotype Reading 57/98; lane 10, negative control, S. enterica serotype Typhimurium 798; lane 11, labeled lambda marker (23, 9.4, 6.5, 4.3, 2.3, and 2.0 kb). The arrow indicates native plasmid hybridization.

Similar articles

Cited by

References

    1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. More, J. G. Seidman, J. A. Smith, and K. Stzubl. 1993. Current protocols in molecular biology. John Wiley and Sons, Inc., New York, N.Y.
    1. Barnaud, G., G. Arlet, C. Verdet, O. Gaillot, P. H. Lagrange, and A. Philippon. 1998. Salmonella enteritidis: AmpC plasmid-mediated inducible β-lactamase (DHA-1) with an ampR gene from Morganella morganii. Antimicrob. Agents Chemother. 42:2352-2358. - PMC - PubMed
    1. Bauernfeind, A., I. Stemplinger, R. Jungwirth, and H. Giamarllou. 1996. Characterization of the plasmidic β-lactamase CMY-2, which is responsible for cephamycin resistance. Antimicrob. Agents Chemother. 40:221-224. - PMC - PubMed
    1. Bryan, J. P., and W. M. Scheld. 1992. Therapy of experimental meningitis due to Salmonella enteritidis. Antimicrob. Agents Chemother. 36:949-954. - PMC - PubMed
    1. Carattoli, A., F. Tosini, W. P. Giles, M. E. Rupp, S. H. Hinrichs, F. J. Angulo T. J. Barrett, P. D. Fey. 2002. Characterization of plasmids carrying CMY-2 from expanded-spectrum cephalosporin-resistant Salmonella strains isolated in the United States between 1996 and 1998. Antimicrob. Agents Chemother. 46:1269-1272. - PMC - PubMed