Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Feb;11(2):50-6.
doi: 10.1016/0169-4758(95)80116-2.

T-cell activation and the balance of antibody isotypes in human lymphatic filariasis

R M Maizels  1 , E Sartono, A Kurniawan, F Partono, M E Selkirk, M Yazdanbakhsh
Affiliations

T-cell activation and the balance of antibody isotypes in human lymphatic filariasis

R M Maizels et al. Parasitol Today. 1995 Feb.

Abstract

Human filarial infection presents a spectrum of clinical states with two major poles: asymptomatic microfilaraemia and amicrofilaraemic chronic disease. Microfilaremia is associated with a Th1-type tolerance, and maximal IgG4 antibodies, while elephantiasis patients react across a broad range of immune parameters. In this review, Rick Maizels and his colleagues discuss recent advances in the immunology of human filariasis and present a summary of their latest studies in an endemic area of Indonesia.

PubMed Disclaimer

LinkOut - more resources