New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity
- PMID: 15278142
- DOI: 10.1039/b406076h
New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity
Abstract
The first biologically active non-planar analogues of the toxic anti-cancer agent, fascaplysin, have been produced; we present the design, synthesis and biological activity of three tryptamine derivatives.
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