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. 2004 Aug 7:(15):1696-7.
doi: 10.1039/b406076h. Epub 2004 Jun 25.

New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity

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New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity

Carine Aubry et al. Chem Commun (Camb). .

Abstract

The first biologically active non-planar analogues of the toxic anti-cancer agent, fascaplysin, have been produced; we present the design, synthesis and biological activity of three tryptamine derivatives.

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