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. 2004 Aug 7;2(15):2137-52.
doi: 10.1039/b405839a. Epub 2004 Jul 14.

The merger of natural product synthesis and medicinal chemistry: on the chemistry and chemical biology of epothilones

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The merger of natural product synthesis and medicinal chemistry: on the chemistry and chemical biology of epothilones

Karl-Heinz Altmann. Org Biomol Chem. .

Abstract

Based on epothilones as powerful natural product leads several promising new anticancer agents have emerged through concerted efforts in chemistry and biology.

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