Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Aug 5;6(16):2769-72.
doi: 10.1021/ol049030n.

Selective mono-O-acylation of C2V-symmetrical calix[4]arenediols with acylisocyanates

Anton V Yakovenko  1 , Vyacheslav I Boyko, Oleg V Kushnir, Ivan F Tsymbal, Janusz Lipkowski, Alexander Shivanyuk, Vitaly I Kalchenko
Affiliations

Selective mono-O-acylation of C2V-symmetrical calix[4]arenediols with acylisocyanates

Anton V Yakovenko et al. Org Lett. .

Abstract

Calix[4]arenedialkyl ethers 3 react with an excess of acylisocyanates to give selectively monoacylated products 4. Intramolecular hydrogen bonds and steric effects of the acylcarbamate fragments are most likely responsible for the high selectivity of this monoprotection. [reaction: see text]

PubMed Disclaimer

LinkOut - more resources