doi: 10.1021/ol048891t.
Palladium-catalyzed allylalkynylation of benzynes: a highly efficient route to substituted 1-allyl-2-alkynylbenzenes
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- PMID: 15281778
- DOI: 10.1021/ol048891t
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Palladium-catalyzed allylalkynylation of benzynes: a highly efficient route to substituted 1-allyl-2-alkynylbenzenes
Org Lett.
.
Abstract
Benzynes, generated in situ from 2-(trimethylsilyl)aryl triflates and cesium fluoride, undergo allylalkynylation with allylic chlorides and alkynylstannanes in the presence of palladium catalyst to give 1-allyl-2-alkynylbenzenes in good to excellent yields. [reaction: see text]
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