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. 2004 Mar;39(3):139-42.

[Effect of endoscopic sinus surgery on asthmatic patients with chronic sinusitis and nasal polyps]

[Article in Chinese]
Su-ling Hong  1 , Jiang-ju Huang, Yu-cheng Yang, Hou-yong Kang, Yi-qin Wang, Rong Sun, Di Qian, Xiao-qin Dong
Affiliations
  • PMID: 15283291

[Effect of endoscopic sinus surgery on asthmatic patients with chronic sinusitis and nasal polyps]

[Article in Chinese]
Su-ling Hong et al. Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004 Mar.

Abstract

Objectives: To explore the effect of endoscopic sinus surgery (ESS) in patients with chronic rhinosinusitis and asthma.

Methods: Forty-two patients with asthma who underwent ESS and control group were investigated. Interleukin-4 (IL-4), interferon-gamma (IFN-gamma), soluble interleukin-2 receptor (sIL-2R) and soluble CD23 (sCD23) levels in culture supernatant of peripheral blood mononuclear cell (PBMC) were determined by enzyme-linked immunosorbent assay (ELISA).

Results: Of these 42 patients 32 (76%), their asthma was relieved greatly after ESS comparing with that before ESS. 14 of 21 patients (67%) taken regular medication for asthma before ESS reported that less medicine was used after operation.

Conclusion: This study demonstrates that ESS has a favorable effect on asthma in patients with symptomatic chronic sinusitis.

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