Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2004 Jun;45(6):507-10.

Challenging diagnosis--icterus associated with a single perforating duodenal ulcer after long-term nonsteroidal antiinflammatory drug administration in a dog

Felix M Duerr  1 , Anthony P Carr, Trevor N Bebchuk, Neil C Pople
Affiliations
Case Reports

Challenging diagnosis--icterus associated with a single perforating duodenal ulcer after long-term nonsteroidal antiinflammatory drug administration in a dog

Felix M Duerr et al. Can Vet J. 2004 Jun.

Abstract
in English, French

A dog developed icterus, vomiting, and anorexia 2 wk after orthopedic surgery and treatment with meloxicam for approximately 1 y. Exploratory laparotomy revealed a single perforated duodenal ulcer. The most likely cause of the hyperbilirubinemia was intrahepatic cholestasis resulting from peritonitis associated with the perforation.

Résumé — Diagnostic contestable — Ictère associé à un ulcère duodénal perforant unique à la suite de l’administration à long terme d’un anti-inflammatoire non stéroïdien chez un chien. Un chien a présenté de l’ictère, des vomissements et de l’anorexie 2 semaines après avoir subit une chirurgie orthopédique et après avoir été traité pendant environ 1 an au méloxicam. Une laparotomie a révélé un ulcère duodénal perforé unique. La cause la plus probable de l’hyperbilirubinémie était une cholestase intrahépatique provoquée par une péritonite associée à la perforation.

(Traduit par Docteur André Blouin)

PubMed Disclaimer

Figures

Figure 1
Figure 1
Peritoneal effusion located in the region of the liver.
Figure 2
Figure 2
“Sludge” in the gall bladder.
See this image and copyright information in PMC

Comment in

Similar articles

See all similar articles

Cited by

References

    1. Hall JA. Diseases of the stomach. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine. 5th ed. vol 2. Philadelphia: WB Saunders, 2000:1154–1182.
    1. Hinton LE, McLoughlin MA, Johnson SE, Weisbrode SE. Spontaneous gastroduodenal perforation in 16 dogs and seven cats (1982–1999) J Am Anim Hosp Assoc. 2002;38:176–187. - PubMed
    1. Forsyth SF, Guilford WG, Lawoko CRO. Endoscopic evaluation of the gastroduodenal mucosa following non-steroidal antiinflammatory drug administration in the dog. N Z Vet J. 1996;44:179–181. - PubMed
    1. Forsyth SF, Guilford WG, Haslett SJ, et al. Endoscopy of the gastroduodenal mucosa after carprofen, meloxicam and ketoprofen administration in dogs. J Small Anim Pract. 1998;39:421–424. - PubMed
    1. Reed S. Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler. Can Vet J. 2002;43:971–972. - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources