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. 2004 Aug 6;69(16):5509-11.
doi: 10.1021/jo040164o.

Synthesis of alpha-ketoamides from a carbamoylsilane and acid chlorides

Jianxin Chen  1 , Robert F Cunico
Affiliations

Synthesis of alpha-ketoamides from a carbamoylsilane and acid chlorides

Jianxin Chen et al. J Org Chem. .

Abstract

Treatment of acid chlorides with a carbamoylsilane affords alpha-ketoamides. In some instances, in situ reaction of additional carbamoylsilane with these products yielded alpha-organyl-alpha-siloxymalonamides.

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